Adenovirus pneumonitis successfully treated with intravenous ribavirin.
نویسندگان
چکیده
Adenovirus infections are a frequent cause of severe complications in the post allogeneic bone marrow transplantation period, and to date, no established form of treatment exists. We report the case of an autologous bone marrow transplant recipient who developed adenovirus pneumonitis which was successfully treated with intravenous ribavirin.
منابع مشابه
Intravenous ribavirin treatment for severe adenovirus disease in immunocompromised children.
BACKGROUND Adenovirus is an important cause of morbidity and mortality in the immunocompromised host. The incidence of severe adenovirus disease in pediatrics is increasing in association with growing numbers of immunocompromised children, where case fatality rates as high as 50% to 80% have been reported. There are no approved antiviral agents with proven efficacy for the treatment of severe a...
متن کاملTreatment of adenoviral pneumonitis with intravenous ribavirin and immunoglobulin.
A 67 year old woman developed a severe adenoviral pneumonitis whilst receiving immunosuppressive therapy. She showed clinical and radiological evidence of a response to treatment with nebulised and intravenous ribavirin and intravenous pooled normal human immunoglobulin. To our knowledge this is the first time that such a therapeutic approach has been used in the treatment of a condition which ...
متن کاملTreatment of adenovirus infections in patients undergoing allogeneic hematopoietic stem cell transplantation.
Retrospective analysis of 303 patients who underwent allogeneic hematopoietic stem cell transplantation identified 35 (11.5%) with adenovirus infection. Among them, 22 received specific therapy. As first-line therapy, 18 were treated with intravenous ribavirin, 3 with cidofovir, and 1 with vidarabine. Moreover, 2 received donor leukocyte infusion in combination with ribavirin, and 1 received it...
متن کاملCase report: a fatal case of disseminated adenovirus infection in a non-transplant adult haematology patient
BACKGROUND We report a fatal case of disseminated adenovirus infection in a non-transplant haematology adult patient with chronic lymphocytic leukaemia who had completed combination chemoimmunotherapy a few months before developing respiratory symptoms. In such non-transplant patients, monitoring for adenovirus in the blood is not routine. However, with adenoviruses, when there is a more periph...
متن کاملIntravenous Ribavirin Treatment for Severe Adenovirus Disease in Immunocompromised Children -- Gavin and Katz 110 (1): 9 -- Pediatrics
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عنوان ژورنال:
- Haematologica
دوره 83 12 شماره
صفحات -
تاریخ انتشار 1998